Complex congenital heart disease and pregnancy are a challenge and delicate medical situation.We describe a first-time pregnancy of a woman living with an uncorrected d-transposition of Hoses the great arteries (TGA) with serious fetal complications required multidisciplinary assessment.Twenty-six years old primigravida referred to our cardiology c
Orosomucoid like 3 (ORMDL3) encodes an ER-resident transmembrane protein that regulates the activity of serine palmitoyltransferase (SPT), the first and rate-limiting enzyme for sphingolipid biosynthesis in cells.A decade ago, several genome wide Rack Set association studies revealed single nucleotide polymorphisms associated with increased ORMDL3
Chronic kidney disease (CKD) concerns millions of individuals worldwide, with few therapeutic strategies available to date.Recent evidence suggests that the endocannabinoid system (ECS) could be a new therapeutic target to prevent CKD.ECS combines receptors, cannabinoid receptor type 1 (CB1R) and type 2 (CB2R), and ligands.The most prominent recept
Environmental policy integration is essential in achieving big girls woven pants environmental sustainability goals across non-environmental sectors.Dilution of environmental goals in environmental policy integration should be avoided.The conservation tax incentive of the repealed section 37C(5) read with section 18A of the Income Tax Act 58 of 196